----------------------------------------------------------------------------------------------------------
SEVtras delineates small extracellular vesicles at droplet resolution from single-cell transcriptomes
----------------------------------------------------------------------------------------------------------

**SEVtras** stands for **sEV**\ -con\ **t**\ aining d\ **r**\ oplet identific\ **a**\ tion in **s**\ cRNA-seq data.

You can freely use SEVtras to explore sEV heterogeneity at single droplet, characterize cell type dynamics in light of sEV activity and unlock diagnostic potential of sEVs in concert with cells.

.. image:: ./SEVtras_overview.png
    :width: 800px


Key applications of SEVtras
----------------------------

+ recognize sEVs at single droplet resolution. 
+ calculate sEV secretion activity index (ESAI) for each sampleat tissue. 
+ deconvolve sEV secretion activity into cell type level (ESAI_c). 
+ unlock sEV clinic potential. 


.. toctree::
   :caption: Main
   :maxdepth: 1
   :hidden:

   Overview
   Installation
   Functions

.. toctree::
   :caption: Tutorials
   :maxdepth: 1
   :hidden:

   Part I sEVs recognizing
   Part II ESAI calculating
   Troubleshooting